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Health Articles

Why All People over 50 Should Not Take Lipitor or Cholesterol Drugs For Life!

Brian Bartholomew - Sunday, May 20, 2012

Big pharma 'research' suggests all people over 50 should take statins every day for life

by D Holt 

(NaturalNews) Big pharma propaganda has reached a new height in the UK this week, with the release of a new study that appears to show the benefits of taking statins. The report goes on to claim that everyone over 50 years of age should be taking the drug on a daily basis, for the rest of their lives.

According to the report, the benefits of the statins are to reduce the risks of heart attack and stroke. It then goes on to say that the drug is effective on patients who are classed as not being high risk, but may be smokers, have high blood pressure or are overweight. There are also claims of saving up to 10,000 lives a year, and preventing one third of all heart attacks, strokes and operations on blocked arteries. All this from a drug that would only cost 16 GBP a year per patient in the UK.

While the report does mention that there may be a "slight risk" of the onset of diabetes, it stops short of mentioning some of the even more serious side effects. Side effects range from cataracts, constipation, sexual dysfunction, memory loss, headaches and loss of appetite, to depression, loss of feeling in hands and feet and myopathy. Myopathy is a side effect that affects approximately 1 in every 1,000 users, resulting in pain and tenderness in muscle tissue. This leads to rhabdomyolysis, the breakdown of muscle cells, kidney failure and in some cases death.

Long term use linked to debilitating illness and higher profits

To prescribe statins for every person over the age of 50 in the UK would mean in excess of 20 million people taking these drugs resulting in 20,000 people with myopathy and becoming disabled or dying. This compared to the current number of heart attacks, means that twice the number of people will require hospital treatment. But the pharmaceutical companies will stand to make in excess of 320 million GBP from the UK alone. When put into that context, it is easy to see why this report has been published.

Forcing all people over the age of 50 to take a drug is fundamentally wrong. It flies in the face of the right of all people to choose what they put into their bodies and is an obvious con trick. The goal of the con is to make huge profits out of the industry that has been created around cholesterol levels. If the ratio of LDL to HDL cholesterol is a problem to a patient, it would cost the NHS nothing to prescribe a natural diet with lots of fresh raw fruits and vegetables, without red meat or processed foods. If combined with natural sources of soluble fiber, and daily exercise, the levels of cholesterol would decrease naturally without the need for expensive and dangerous drugs. It seems though that these drugs are aimed at those who want a low LDL to HDL ratio, but want to eat junk and do no exercise. Faced with either painful myopathy or exercising and eating healthy, surely the choice is obvious.

Information for this article can be found at these web sites

http://www.dailymail.co.uk
http://www.naturalnews.com/002692.html
http://www.ninds.nih.gov/disorders/myopathy/myopathy.htm
http://www.agediscrimination.info/statistics/Pages/Statistics.aspx
http://www.patient.co.uk

The Pressure's On! Controlling High Blood Pressure Naturally

Brian Bartholomew - Sunday, February 19, 2012

The Pressure’s On: Preventing High Blood Pressure

Posted By Dr. Axe On December 2, 2009 @ 7:00 am In Heart Disease | 5 Comments

blood pressureThe “epidemics” associated with life in America are most often the result of the western diet and lifestyle. One of the precursors to a host of other epidemic conditions is hypertension or high blood pressure. Hypertension, as high blood pressure is also known, affects 30% of the American population and is a preventable condition. 

The Western lifestyle—diet, low physical activity levels and stress—contributes to a wide variety of chronic diseases and conditions in Americans. These conditions collectively afflict 65% of the adult population in the U.S., while they are rare in cultures that have been isolated from exposure to a western lifestyle.

In fact, as traditional societies begin to adopt western foods and lifestyles, their incidences of chronic conditions such as cancer, diabetes, heart disease, hypertension, obesity and osteoporosis [1] rose dramatically.

An example of this is found in the Canadian Inuit of Nunavik, Quebec. In September of 2009, Dr. Marie-Ludivine Chateau-Degat told the Canadian Cardiovascular Congress that the recent reach of Western foods has severely impacted the health of the natives. The traditional Inuit diet had consisted of fish, seafood, caribou, wild fowl and other marine mammal meat before 1992. The consumption of such a diet included physical labor and activity, the pooling of communal resources, social activities centered around the collective good and social ties, and a diet rich in unprocessed foods, sea salt and other nutrients.

By 2004, store-bought foods had mostly replaced the native diet. 95% of the sodium the Intuits’ now ingest comes from processed foods in the form of highly processed, iodized salt. The majority of carbohydrates they ingest come in the form of sugary drinks. Intake of dietary fiber and essential vitamins and minerals has plummeted, while hypertension, diabetes, heart disease and obesity have soared in the population.

Blood pressure

Most Americans don’t even realize they have high blood pressure until serious problems arise.

Blood pressure is a combination of systolic and diastolic pressure. Systolic pressure represents blood force or pressure while the heart is beating and diastolic pressure stands for blood pressure when the heart is at rest.

Systolic pressure is always the first or top measurement in a blood pressure reading. In a reading of 140/90, 140 represents systolic pressure and 90 represents diastolic pressure. 

In prehypertension, systolic numbers range from 120-139 and diastolic numbers range from 80-89. 

Stage 1 hypertension numbers vary from 140-159 for systolic values and 90-99 in diastolic numbers. 

With Stage 2 hypertension, systolic readings are 160 or higher and diastolic readings measure 100 or higher. 

Although both numbers are significant, after about age 50, the systolic number is most important. Only 10% of high blood pressure cases are due to secondary or identifiable causes such as medications or conditions and diseases of other organs.

Avoid These Like the Plague

High fructose corn syrup [2]? If you eat any packaged foods or sodas, most likely you do, and you’re also more likely to develop hypertension (among other problems) because of it. Americans consume 30% more sugar than they did just 20 years ago and 4 times as much as they did 100 years ago, before the advent of highly processed foods. The obesity rates then were less than 5%, while today 64.5% of American adults are overweight and 30.5% are obese.

Researchers studied 4,528 adults that had no prior history of hypertension.  Those who ingested more than 74 grams of added sugar (about the amount in 2 ½ sugary drinks) daily, led to 28%, 36% and 87% increased risk in high blood pressure readings over time. The percentages correspond to blood pressure readings of 135/85, 140/90 and 160/100.

Another study has looked at American sodium intake. Highly refined salt exists in large amounts in processed foods. The study predicted that reducing sodium intake could eliminate 11 million cases of high blood pressure and save the U.S. $32 billion annually.

Research estimates that more than 77% of America’s sodium intake comes in the form of processed foods rather than salt added to foods while cooking or eating at home. Fast food, another fixture of the western lifestyle, is loaded with sodium. Replace all processed and refined salt with natural sea salt.

Helpful Foods

Potassium: is a compound that seems to protect people from the development of hypertension. Supplements of potassium don’t work well according to research, but foods that contain them do.

Spinach: Spinach is rich in magnesium and folate which can help prevent high blood pressure and cardiovascular disease.

Sunflower Seeds: Rich in potassium, magnesium and healthy plant fats, sunflower seeds can help reduce cholesterol levels, opening up blood vessels and promoting healthy blood pressure.

Bananas: Bananas contain loads of potassium and fiber [3].

Healthy Fats: Oily, cold-water fish provides  omega-3 fatty acids, a healthy balancing technique to the overload of omega-6 and omega-9 fatty acids that are overly prevalent in processed foods, fast and convenient foods and much of the western diet.

Garlic: Research on the health benefits of garlic is finding more and more miraculous effects. Among them, garlic seems to help thin the blood, prevent the blockage in blood vessels, and so lower blood pressure.

Tomatoes: Tomatoes are loaded with calcium, potassium, vitamins A, C and E and lycopene. Compounds in tomatoes can lower cholesterol buildup in blood vessels and combat the development of hypertension in a variety of ways. Lycopene, one of the tomato’s most useful compounds, is activated by heat, so add tomatoes to your next chili or stew.

Broccoli: Broccoli has been found to have a whole host of beneficial health effects including high amounts of potassium and chromium that help regulate blood sugar levels and weight, both related to high blood pressure.

Melon: Melon is rich in potassium. Cantaloupe and watermelon are especially rich sources.

Lifestyle Aids

Regular exercise [4] and diet [5] play a large role in the development (or not) of hypertension. One of the most detrimental components of the western lifestyle is stress.Managing stress [6] includes relaxation techniques such as deep breathing, yoga, journaling or art therapy.

You can raise your blood pressure to alarming levels just by thinking or stressing about events. Imagined events have as much physiological effect as real ones. This is the basis of Post Traumatic Stress Disorder and the improvement of performance in businessmen and Olympic athletic gains with visualization.

The western lifestyle might include career and lifestyle choices that incite chronic disease but that doesn’t mean that you have to proscribe to them. Going against a cultural current takes strength, but the failure of our cultural norm has contributed to the splintering of its route and the availability of alternate paths.

The fight for a culture’s health depends less on science that focuses on finding magical cures in drugs, and more on making fundamental shifts in food production, availability, our connections to food, our work life and stress factors, and re-prioritizing values. The best preventative measure? A healthy lifestyle. It’s common sense, really. With this article and the others on this site, you are now equipped to truly maximize your health.

Dr. Axe

Dr. Axe's Action Steps

  1. Stop the trips to the fast food drive-thru! Eliminate processed foods and sodas that are laden with sugar, high fructose corn syrup, refined salt and unhealthy fats.
  2. Eat a wide variety of foods, focusing especially on adding more vegetables to your diet.
  3. Supplement with 1 Tbsp. of cod liver oil or 1 salmon oil capsule daily and I-2 cloves of garlic daily.
  4. Learn how to recognize and manage stress in your life. Consider making a vision board with your goals. Include pictures and strategies for achieving them.

New Study Low Cholesterol in Elderly Doubles Risk of Early Death

Brian Bartholomew - Thursday, December 22, 2011
New Study Finds that Low Cholesterol in Elderly Doubles Risk of Early Death

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Study finds that elderly with cholesterol less that 189 had a double risk of dying.

Physicians were informed to consider very low levels of cholesterol as potential warning signs of a serious disease or as signals of rapidly declining health.

The study included 4520 men and women between the ages of 65-84.

The study concluded that low total cholesterol was associated with a higher risk of death.

Low cholesterol level is a robust predictor of mortality in the nondemented elderly and may be a surrogate of frailty or subclinical disease according to the research team.

References:
Brescianini S, Maggi S, Farchi G, Mariotti S, Di Carlo A, Baldereschi M, Inzitari D; ILSA Group. Low total cholesterol and increased risk of dying: are low levels clinical warning signs in the elderly? Results from the Italian Longitudinal Study on Aging. J Am Geriatr Soc. 2003 Jul;51(7):991-6.

Schupf N, Costa R, Luchsinger J, Tang MX, Lee JH, Mayeux R. Relationship between plasma lipids and all-cause mortality in nondemented elderly. J Am Geriatr Soc. 2005 Feb;53(2):219-26.

Before prescribing treatment, FMU recommends that you follow the standard of care of your profession, as well as confirm the information contained herein with other sources.

Functional medicine embraces the totality of the regulatory functions of the body. It encompasses all of the biophysical, biochemical, enzymatic, endocrine, immunological, and bioenergetic regulatory capacities.

Dr. Ron Grisanti, D.C., D.A.C.B.O., M.S., D.A.C.B.N.

A Better Approach to Cholesterol Issues, Diabetes, High Blood Pressure or Obesity!

Brian Bartholomew - Thursday, December 15, 2011

A NEW APPROACH TO METABOLIC SYNDROME
By: Michael P. Ciell, R.Ph.,

The Greatest Healthcare/Financial Crisis

Metabolic Syndrome (aka Syndrome X) with its four hallmark symptoms of obesity, hypertension, dyslipidemia and hyperglycemia is devastating our country as well as the whole of North America. In March of 2005 the National Institutes of Health and the New England Journal of Medicine published a paper stating that because of this epidemic the current generation is projected to have a shorter life expectancy then the previous one…for the first time in recorded history! Since that paper things have become much worse. Worse, despite the fact we have changed the USDA “Food Pyramid”, developed many new classes of pharmaceutical agents (especially ones for pre-diabetes and diabetes Type II), have taken soda machines out of schools, and even the First Lady’s top priority is the obesity epidemic. This syndrome, with all of its comorbidities (cardiovascular disease, stroke, many cancers, kidney failure, blindness, amputations ,etc.), accounts for the majority of healthcare dollars spent. If the tide is not turned, Metabolic Syndrome will bankrupt our country. This is a fact.

The Pathophysiology of Metabolic Syndrome
In 1987 the late Gerald Reaven, MD, Professor of Medicine at Stanford University’s College of Medicine, first demonstrated that the four hallmark symptoms shared a commonality: hyper-insulinemia coupled with insulin resistance. He coined the term “Syndrome X” to illustrate the point: the four legs of the “X” represent the symptoms (hypertension, central obesity, hyperglycemia and dyslipidemia) and the nexus of the “X” being the causal agents of too much insulin along with insulin resistance (the cells’ do not respond to normal physiologic amounts of insulin). This is the standard, accepted medical model of this disease.

The Failure of Current Treatments
We are being ravaged by this syndrome due to the simple fact that we have ignored the model! Instead of focusing our attention on the root cause we have decided to treat each of the symptoms as separate, unrelated diseases. Thus we have new dietary recommendations and “diets d’Jour”, as well as a plethora of exercise regimens prescribed for obesity and of course, the “diet pills”. There too are the myriad of prescription drugs to ‘control’ the other three symptoms. If our attention is on ‘controlling symptoms’ we have admitted, by default, that there is NOTHING WE CAN DO FOR THE CAUSATIVE FACTORS and we will just have to LEARN TO LIVE WITH OUR DISEASE (i.e. ‘it will always be with us, we’ll just control it’). This attitude of acceptance is bad enough and unaffordable in the long run, but that’s the least of it. If we understand the pathophysiology of this syndrome we readily can see why many of these treatments actually make the other symptoms much worse! Hyper-insulinemia means the patient’s pancreas is secreting an exaggerated amount of insulin in response to rises in blood glucose. This can easily be confirmed by doing a fasting insulin level OR the standard glucose challenge test and ordering insulin levels along with glucose levels at time zero, one hour and two hour intervals post challenge glucose administration.

Sadly, the vast majority of practitioners do not even think about such an important marker. So we dwell on just the glucose level or Hemoglobin A1c (merely symptoms ) and prescribe drugs such as the sulfonylureas (i.e. glyburide, glipizide, glimperide) which cause the pancreas to secrete EVEN MORE INSULIN or we actually give them INSULIN ITSELF in an aggressive attempt to control a symptom. If the model is correct then this therapy should make the syndrome worse……and it does! This is the fundamental reason why we have failed to stem the tide (or actually reverse) this seemingly insidious malady.

The Concept of Homeostasis
If insulin just mediated glucose uptake by our cells and did nothing else, we probably would not have this problem. However this is not the case and when the amount of insulin remains consistently elevated it does other things…..and these things are NOT good. Before discussing the effects of hyper-insulinemia, a review of the fundamental concept of homeostasis should be addressed.

The body is an organism that strives to maintain a constant internal environment in the face of constantly changing, often hostile, external factors. Blood pressure, blood glucose, body temperature, acid / base balance, etc. must remain within a relatively narrow range in order to survive. It does so by means of the action/reaction principle, or mechanisms that exert opposite effects so that a balance may be
achieved. Examples are: vasodilation / vasoconstriction, oxidation / reduction, anabolism/catabolism, assimilation / elimination, etc. These systems are exquisitely regulated primarily by the nervous system and the endocrine (hormonal) system. So if the environmental temperature is 125 degrees, our internal temperature remains at 98.6 degrees. Likewise if the temperature drops to 20 degrees, certain mechanisms are in place to make certain our internal temperature remains a constant 98.6. Glucose homeostasis is essential for life as certain cells in the body can only use glucose as an energy source (certain brain cells, the adrenal medulla, red blood cells, etc.). Whether in times of feast or famine, blood glucose must remain in a certain range and insulin and glucagon are the master hormones that control this process (forget about ghrelin, leptin, incretins and all these ‘new mini-hormones’ that are in the literature today…these are subservient to the two masters). The body needs BOTH of these “master hormones” to maintain balance ( as they have exactly opposite physiological functions….if you know what insulin does, then you automatically know what glucagon does…the exact opposite!) and if an imbalance occurs, dysfunction or “disease” will arise.

The Physiological Effects of Insulin
Insulin’s primary function is mediating glucose uptake to muscle cells, and in this way, helps regulate blood glucose homeostasis. However insulin binds to many other receptors in the body and affects MANY other physiological parameters. And here’s the “rub”. If insulin receptors on the muscle cells become resistant to insulin’s effect (and do not uptake glucose in an effective manner) the pancreas will produce more to ensure glucose uptake will occur. But if we increase insulin levels, what happens to OTHER receptors that are not “resistant” yet and modulate other bodily functions? This scenario becomes way more complicated, in that, these receptors become ‘insulin resistant’ at different times. So a ‘typical Syndrome Xer’ presents to the physician with some central obesity, slightly elevated blood pressure, slightly elevated blood glucose and a less than stellar lipid panel. He is told to lose some weight by eating more fruits and vegetables, cut down on fats and cholesterol (have oatmeal instead of bacon and eggs) and do some light exercise. This is standard, first line therapy of lifestyle changes and sounds very reasonable. This compliant patient makes these changes and returns in two months, shocked and disappointed that his symptoms have become worse! Now he is given a low dose ACE inhibitor coupled with a diuretic for his hypertension and placed on metformin and glyburide to help control hyperglycemia. The glyburide tells the pancreas to secrete even more insulin and he gains more weight. Insulin also “ramps up” the enzyme HMG-Co A reductase which basically tells the body to produce even more cholesterol.

Excess insulin also drives the kidneys to retain sodium and waste magnesium,
which is an essential element for insulin receptor sensitivity. Hypertension and insulin resistance worsen. Usually at this point (if not done sooner) a statin is added along with niacin and another oral hypoglycemic and we ‘start the march’ to insulin therapy. This is why many of these patients will find themselves on six to nine prescription drugs and this is the current “Standard of Care” for this syndrome.

Let Your Food Be Your Medicine
Let us now suppose that the above patient visited a Chiropractic physician first. This particular physician is skilled in the use of a ‘muscle sparing’ protein diet, not a hyper protein diet ala Atkins. This diet is also low in fat, particularly saturated fat and is very carbohydrate restrictive (providing about 40 grams of carbohydrates daily mainly from fibrous vegetables). The physician explains the “medical model” of Syndrome X and relates how the overproduction of insulin can contribute to all his symptoms.

Correcting hyperinsulinemia is very straightforward: all carbohydrates (with the exception of fiber) will eventually be turned into glucose….sometimes quickly, sometimes slowly. As the glucose is absorbed the pancreas begins to secrete insulin (in this case, too much insulin). By restricting the carbohydrates the production of insulin is immediately reduced. The patient is interested but confides that he can be hypoglycemic at times and is afraid of such a restrictive protocol. The physician relates that hypoglycemia is usually the consequence of an overproduction of insulin, not a lack of carbohydrates. He further explains the body has “three tanks of energy” from which to draw. Glycogen (or our stored glucose), muscle, which can be broken down via gluconeogenesis to supply glucose and fat (triglycerides) which can be turned into glucose (from the glycerol) and ketonic bodies which most of the cells In the body can use for fuel. But the body draws on these compartments in a very specific order. It will always use the glycogen first and only when ‘that tank’ is empty, will it then begin to simultaneously burn muscle and fat.

The physician tells the patient if he keeps “putting fuel in the glycogen tank”, he will never be able to access his fat reserves, thus the restriction of carbohydrates. He also says that we never want to lose muscle, thus the inclusion of the adequate amount of protein to replenish what is lost to gluconeogenesis. During the first three days of this protocol the patient may feel a little tired or weak (as the body depletes its glycogen) but once this is gone and the body ‘switches over to muscle and fat’, he will have plenty of energy and hypoglycemic episodes will be a thing of the past. His patient is interested but asks: “ketonic bodies”, does that mean ketosis…I thought that was bad?” Again the physician explains that ketoacidosis is bad and that is why a Type I diabetic would never be placed on this program. In this case ketosis just means ‘living off your reserves’ and is the reason human beings were able to survive times of famines. His concerns allayed, the patient begins the program.

Under The Influence Of Glucagon

Six weeks later the elated patient returns to his Chiropractor. He is thirty pounds lighter and says that his medical doctor told him his blood work was fantastic! In layman’s terms the physician tells him: “Well you have actually reset your pancreas, it no longer is pumping out too much insulin and now you can start to put fruits, grains and dairy back into your diet”. After this patient’s glycogen reserves were depleted and carbohydrates continued to be restricted, the body had to ensure proper blood glucose levels were maintained. Under these conditions the pancreas produces more glucagon (which raises blood sugar) and much less insulin (whose primary function is to lower blood sugar).

But there is more to glucagon than this primary function. Glucagon stimulates two adipocyte (fat cell) enzymes (HSL and ATGL) and inhibits a third (Lipoprotein lipase). The result is the release of trigylcerides from the fat cell (to be used a fuel) as opposed to insulin’s effect which is to store fat. Glucagon enhances the entry of free fatty acids across the mitochondrial membranes so they can be used as fuel (insulin inhibits this). Glucagon also greatly inhibits the action of HMG-CoA reductase (along with all the other enzymes necessary for cholesterol synthesis) and forces cells to pull cholesterol from the blood stream via ‘ramping-up’ LDL receptors (1983 Nobel Prize in Medicine). This is why this patient’s lipid panel came back stellar. Finally in the kidneys the retention of sodium (caused by excess insulin) has now been corrected and his hypertension has resolved. The pathophysiology of Syndrome X is predictable. The reversal of this syndrome is also predictable and repeatable! As a matter of fact this exact method is being employed by over 700 chiropractic practices in the United States and Canada as well as many medical practices. Tens of thousands of patients have experienced same benefits described here.

The Chiropractic physician (because of his/her training and philosophy) can become a leading force in helping to reverse this terrible syndrome. Let this article be a call to action!

Bypass That Operation

Brian Bartholomew - Friday, December 09, 2011

Bypass That Operation?

Each year doctors perform 400,000 bypass surgeries and 1 million angioplasties, where mesh tubes are placed in diseased arteries to hold them open. While most people believe that such surgery is life-saving, the available data say otherwise. 

Except for about 3% of people with severe heart disease, treatment with drugs alone works just as well to extend life and prevent heart attacks as surgery does. "Cardiologists like to open up arteries," says Dr. David D. Waters, chief of cardiology at San Francisco General Hospital. "But there is no evidence that opening up chronically narrowed arteries reduces the risk of heart attack." Harvard Medical School's Dr. Roger J. Laham figures that at least 400,000 angioplasties a year are unnecessary. "I'm sure we are way overtreating our patients," he says. Surgery carries big risks, such as mental declines after bypass operations. The overuse is exacting a big toll on individual patients and the health-care system, argue such experts as Dr. Nortin M. Hadler, professor of medicine at the University of North Carolina at Chapel Hill.

The Dark Truth About Cholesterol Drugs

Brian Bartholomew - Wednesday, October 26, 2011

The Dark Truth About the "Wonder Drug" Millions Swear By

Posted By Dr. Mercola | October 26 2011 | 

Story at-a-glance

  • Statin drug side effects can easily be misdiagnosed as unrelated health problems, which leads to polypharmacy and unnecessary drug treatments.
  • Statins are known to cause nerve- and muscle damage, and are contraindicated during pregnancy due to high risk of birth defects. They can also lead to a number of other health complications.
  • The true dangers of statin drugs, which suppress the synthesis of cholesterol, are becoming increasingly apparent. Dr. Seneff provides a dozen sources for you to review to increase your knowledge base about this hazardous drug.

By Dr. Stephanie Seneff

The trials that a new drug goes through can only achieve limited testing, and, almost always, the tests used to evaluate the side effects of a drug are too short due to expediency and cost. It is only once a drug is unleashed upon the real world, and enough time passes, that we learn how its toxic effects can manifest themselves after years of treatment.

Fortunately, the internet holds the key to answers obtained by millions of patients who have unwittingly offered themselves up as guinea pigs in the experiment of living long-term with a given drug.

Statin drugs are particularly problematic because they suppress the synthesis of a biological wonder drug, namely cholesterol.

Repeatedly, retrospective studies have shown an alleged benefit for statins, which is actually a benefit derived from the many years of high cholesterol that preceded statin treatment.

This game has been played out for sepsis, pneumonia, multiple sclerosis, diabetes, and Alzheimer's, and these are just the ones I'm aware of.

When the proper placebo-controlled study is done, the effect reverses -- statins make the situation worse.

But these negative results are kept well concealed from the public's eyes. This is how the myth has been kept alive that statins, instead of cholesterol, are the wonder drug.

Below are 13 links to Web sites that contain useful information about statin drugs and cholesterol. Spend some time perusing these links, and then you will be better informed to decide for yourself whether or not to take a statin drug.

#1. Biological Mechanisms Behind Statin Side EffectsDuane Graveline, the M.D. who goes by the nickname "Spacedoc" has done everything he can to inform the public of the dangers of statin drugs. Dr. Graveline is a former NASA astronaut and Air Force flight surgeon. His reasons for taking on the challenge of debunking statins are very personal, because he developed global transient amnesia while taking Lipitor, an unnerving experience that deprives you of all memory of events in your life looking back several decades.

Since then, he has conducted extensive research on the biological mechanisms behind the diverse severe side effects of statin drugs. The link above is but one branch of a vast network of frightening yet informative information about the potentially devastating long-term effects of statin therapy.

#2. Statins and Nerve DamageThe People's Pharmacy is a wonderful forum that allows patients to share their experience. This is one of many examples of adverse side effects of statin drugsavailable on that site.

#3. Statins and Pregnancy: Like thalidomide, statin drugs are a class X drug with regard to pregnancy, meaning they are contraindicated and should NOT be taken by pregnant women. They can cause significant damage to the nervous system of a developing embryo.

#4. New York Times  Exposes Potential for Misdiagnosis Caused by Statin Use: This article points out some of the severe side effects statins can cause, and illustrates with a poignant story about a woman from Kansas. She had been taking a statin for years to reduce her cholesterol. Over that same time period, she experienced chronic muscle pain which neither she nor her doctor attributed to the statin therapy. It even led to a useless shoulder operation.

Her problem eventually escalated into skin lesions caused by a reaction to toxic protein by-products released by her disintegrating muscles. She was given an antifungal to treat the skin lesions, another misdiagnosis. But the antifungal interacted with the statins to further increase the severity of her muscle disorders. Three months later, she could barely stand, and her pulmonary muscles were so weak she couldn't breathe. She died shortly thereafter.

#5. The International Network of Cholesterol Skeptics (THINCS)Dr. Uffe Ravnskov has campaigned tirelessly to fight the myth that high cholesterol is damaging to your health. This web page contains valuable information about all the ways in which cholesterol keeps you healthy.

#6. The ASEPSIS TrialThe statin industry continues to claim that statins protect against sepsis because of several retrospective studies that show that those who take statins have less risk than those who don't.

What these studies are proving is that cholesterol protects from sepsis. The media keep saying that what is needed is a double-blind placebo controlled study, but they already have one they could talk about. It's just that you can't find out anything about it except that it was completed in January, 2008. You can read my take on statins and sepsis here.

#7. Statins Increase Pneumonia RiskJust as for sepsis, the statin industry likes to claim that statins improve your chances against pneumonia. But a double-blind placebo controlled study proved them wrong. The risk for pneumonia that required hospitalization was increased by 61 percent in the statin group compared to the controls.

#8. WebMD Article on Muscle Pain and Weakness: This relatively benign article on WebMD provoked a firestorm of responses; each comment tells the story of another tragedy unfolding. To understand the biological mechanism behind the process by which statin drugs destroy muscles, see this link.

Here's a typical comment from that site:

"I was prescribed Crestor 20mg 2 weeks ago with cholesterol level 7.6. First time on any medication. After approx. 4 days I started to experience severe muscle pain, thigh, buttocks, arms, legs to the extent that I can hardly get out of bed in the morning. Have been back to Dr. who advised stopping tablets. Have been off them for 3 days, very little difference. I am hoping these pains will go away soon. I will never take a statin drug again - would rather take the healthy option, diet and exercise and take the risk. Have never felt so bad. Usually very healthy, fit person."

#9. Statins and Heart Failure: Dr. Peter Langsjoen believes that statin drugs greatly increase your risk of heart failure. I have argued why this might be true here.

#10. JUPITER Trial and DiabetesThe JUPITER trial, which was terminated prematurely after less than two years, was widely heralded for showing that statins reduce the risk of heart attacks in the short term for people with high levels of C-reactive protein but without high cholesterol.

However, little note was made of the fact that the JUPITER trial also showed a 25 percent increased risk to new-onset diabetes in the treatment group. Since diabetes is a strong risk factor for heart disease, one wonders how the trial would have turned out if it had been allowed to run to completion.

#11. High Cholesterol and Alzheimer'sThis is the article that inspired the Newsweek article, #12 below, with the lead story that statins "protect from" Alzheimer's -- which is the exact opposite of the truth about statins and Alzheimer's.

The only relationship between high cholesterol and Alzheimer's the authors could find was if they looked back 30 years. What they're not saying is that, in the intervening years, cholesterol levels fell for those who later developed Alzheimer's. While no one has said exactly why their levels might have fallen, statin drugs are a good bet.

Here's the only thing that the article above has to say about statin drugs:

"Information on lipid-lowering treatments, which have been suggested to decrease dementia risk, was not available for this study."

You can be sure that, if there was any inkling that the statins might have helped, these researchers would have been allowed access to those statin treatment data. You can read my essay on statins and Alzheimer's to learn why statins would likely cause Alzheimer's.

#12. Glowing Newsweek Article on Statins:This article illustrates how thoroughly the statin industry has succeeded in brainwashing the media into believing that black is white. The lead story is that statins protect against Alzheimer's. If you have read my essay on statins and Alzheimer's, you will think otherwise.

The only two placebo-controlled studies mentioned in that article were "underway" at the time. Interestingly enough, the media have kept mum on one of these studies: "S5-01-05: Multi-center, randomized, double-blind, placebo-controlled trial of Simvastatin to slow the progression of Alzheimer's disease," Alzheimer's Association International Conference on Alzheimer's Disease, Volume 4, Issue 4, Supplement 1, July 2008, Page T200, now that it's done. I wonder why?? Unfortunately, there's not even an abstract available in the public domain for this study.

The other study, on multiple scerosis, failed due to the fact that they couldn't get enough people to agree to participate. I think people with multiple sclerosis were wise to stay away from it. Here's an article that shows that statins increase damage in multiple sclerosis.

About the Author:

Dr. Stephanie Seneff is a senior scientist at MIT and has been conducting research there for over three decades. She also has an undergraduate degree in biology from MIT, and a minor in food and nutrition. She's affiliated with the Weston A. Price Foundation.

From Eggs to Statins, What Your Doctor Didn’t Tell You About Cholesterol

Brian Bartholomew - Thursday, July 28, 2011

Cholesterol Deceptions: 
From Eggs to Statins, 
What Your Doctor Didn’t Tell You About Cholesterol
© 2011 Health Realizations, Inc.


Over 16 percent of U.S. adults have high cholesterol, defined as 240 mg/dL and above, according to the U.S. Centers for Disease Control and Prevention (CDC). Even the average level for Americans, 200 mg/dL, is borderline high, they say.

 

Some experts believe statin drugs are vastly overprescribed and could be leading Americans to unnecessarily lower their cholesterol to dangerously low levels.

This high cholesterol, public health agencies say, is putting people at an increased risk of heart disease, the leading cause of death in the United States. This stated “fact” scares millions of Americans into take statin cholesterol-lowering drugs to get their levels as low as possible … but what if this “fact” was actually not true?

Does Cholesterol Cause Heart Disease?

Cholesterol is actually an essential part of your body, used to produce cell membranes, steroid hormones, vitamin D and the bile acids your body needs to digest fat. Your brain needs cholesterol to function properly, as does your immune system, and if a cell becomes damaged, it needs cholesterol in order to be repaired.

In fact, making excess cholesterol is actually your body’s response to inflammation, which it does to help heal and repair your cells. So if you have high cholesterol you probably have high inflammation levels too (more on this later).

Many Americans are under the mistaken impression that all cholesterol is bad, but in reality cholesterol is good for your body and necessary for you to live. Unfortunately, the “lipid hypothesis” (aka the “diet-heart hypothesis”), the one that claims foods high in saturated fats drive up your cholesterol levels, which clog your arteries and lead to heart disease, is widely accepted and has helped to spread the misinformation about cholesterol throughout the public.

But the lipid hypothesis is actually seriously flawed.

In his book The Cholesterol Myths, Uffe Ravnskov, MD, PhD explained that Ancel Keys, who performed the study upon which the Lipid Hypothesis is based, used cherry-picked data to prove his point that countries with the highest intake of animal fat have the highest rates of heart disease.

Dr. Ravnskov revealed that the countries used in the study were handpicked, and those that did NOT show that eating a lot of animal fat lead to higher rates of heart disease were left out of the study, leading to entirely skewed, and faulty, data.

One recent study even found that there is no association between eating saturated fat (which is supposed to drive up cholesterol levels) and heart disease. The authors wrote:

“According to the classic ‘diet-heart’ hypothesis, high intake of SFAs [saturated fats] and cholesterol and low intake of PUFAs [polyunsaturated fats] increase serum cholesterol levels and risk of CHD [coronary heart disease].

However, few within-population studies have been able to demonstrate consistent associations with any specific dietary lipids, with the exception of trans fats and omega–3 fatty acids.

The available evidence from Cohort and randomized controlled trials is unsatisfactory and unreliable to make judgment about and substantiate the effects of dietary fat on risk of CHD … There is probably no direct relation between total fat intake and risk of CHD.”

Does This Mean You Can Eat Eggs Again?

If you’ve been shunning eggs because you fear they will raise your cholesterol, you needn’t avoid this healthy protein source any longer.

For starters, eating cholesterol is not what gives you high cholesterol. According to the Harvard Heart Letter, it’s a myth that all the cholesterol in eggs goes into your bloodstream and your arteries.

“For most people, only a small amount of the cholesterol in food passes into the blood,” the Heart Letter states. “The only large study to look at the impact of egg consumption on heart disease—not on cholesterol levels or other intermediaries—found no connection between the two.”

Eggs are also an excellent source of healthy nutrients, including choline, a B vitamin that may help reduce your risk of heart disease, cancer, dementia and more. Egg yolks also provide the most readily absorbed form of lutein, a yellow-hued carotenoid that may help fight everything from cancer and cataracts to macular degeneration and aging.

For more information, be sure to read The Truth About Eggs: How to Tell the Good From the Bad

Is it true that eating eggs will give you heart disease? No! The only large study to look at the link between eggs and heart disease found no connection.

What is Actually High When it Comes to Cholesterol?

Not only does evidence suggest that saturated fat does not cause heart disease by way of high cholesterol, but there is considerable questioning of what actually constitutes “high” cholesterol in the first place.

The American Heart Association states, “About half of American adults have levels that are too high (200 mg/dL or higher) and about 1 in 5 has a level in the high-risk zone (240 mg/dL or higher).”

But according to lipid biochemistry expert Mary Enig, PhD in the Weston A. Price Foundation quarterly magazine:

“Blood cholesterol levels between 200 and 240 mg/dl are normal. These levels have always been normal. In older women, serum cholesterol levels greatly above these numbers are also quite normal, and in fact they have been shown to be associated with longevity.

Since 1984, however, in the United States and other parts of the western world, these normal numbers have been treated as if they were an indication of a disease in progress or a potential for disease in the future.”

What this means is that many Americans may be taking statin cholesterol-lowering drugs unnecessarily, believing their cholesterol is dangerously high when it is not.

Statin Drugs: Is Modern Medicine’s Cure-All Harming Your Health?

Cholesterol-lowering drugs known as statins are among the most commonly prescribed drugs in the United States.

They work by interfering with an enzyme that your body needs to make cholesterol. Along with lowering cholesterol, the drugs -- which include Lipitor, Zocor, Mevacor, Pravachol, Crestor and others -- may also help your body reabsorb cholesterol that has accumulated on your artery walls, helping to prevent further blockage.

However, although cholesterol drugs do lower cholesterol, there is question over whether or not they actually lower your risk of heart disease.

For instance, as Business Week reported, James M. Wright, a physician and professor at the University of British Columbia, analyzed evidence from years of trials with statins and was surprised at what he found among data from patients with no heart disease who were taking the drugs:

He found no benefit in people over the age of 65, no matter how much their cholesterol declines, and no benefit in women of any age. He did see a small reduction in the number of heart attacks for middle-aged men taking statins in clinical trials.

But even for these men, there was no overall reduction in total deaths or illnesses requiring hospitalization—despite big reductions in "bad" cholesterol. "Most people are taking something with no chance of benefit and a risk of harm," says Wright.”

As Business Week continued, when you look at the fine print of data surrounding cholesterol drugs, the benefits often altogether disappear. Referring to one figure stated by drug maker Pfizer, which said 3 percent of patients taking a placebo had a heart attack compared to 2 percent of patients on the statin drug Lipitor:

“The numbers in that sentence mean that for every 100 people in the trial, which lasted 3 1/3 years, three people on placebos and two people on Lipitor had heart attacks.

The difference credited to the drug? One fewer heart attack per 100 people.

So to spare one person a heart attack, 100 people had to take Lipitor for more than three years. The other 99 got no measurable benefit.”

Suddenly the drugs don’t sound so miraculous, do they?

They also carry steep risks.

In one of the most revealing looks into the true side effects of statin drugs, a review published in the American Journal of Cardiovascular Drugs found nearly 900 studies of adverse effects linked to the drugs.

"Muscle problems are the best known of statin drugs' adverse side effects," Beatrice Golomb, MD, PhD, associate professor of medicine at the University of California, San Diego School of Medicine and co-author of the study, told EurekAlert. "But cognitive problems and peripheral neuropathy, or pain or numbness in the extremities like fingers and toes, are also widely reported."

Other side effects included increases in blood glucose levels, tendon problems and an increase in liver enzymes, leading to permanent liver damage. Because of this latter risk, people taking the drugs must have their liver function tested periodically.

Nausea, diarrhea, abdominal pain, constipation, headaches and skin rash are other known side effects.

Statin drugs are also known to block the production of important nutrients in your body, including CoQ10, which is beneficial to heart health and muscle function. If CoQ10 levels become depleted, which is common in those who take statin drugs, it can actually cause heart failure.

So What is the Best Way to Maintain Healthy Cholesterol Levels?

Eating lots of fast food can lead to chronic inflammation in your body, which is a trigger for your system to make more cholesterol. If you want to lower your cholesterol, cutting out fast food … to curb the underlying cause of inflammation … is a wise first step.

Remember the inflammation connection? Your body tends to make more cholesterol when it’s in a chronically inflamed state. What causes the underlying inflammation?

Inflammation is often due to poor diet and the consumption of processed foods or lack of live healthy raw foods. For instance, if you eat a lot of fast food, you probably have increased inflammation levels, as pro-inflammatory foods include sugar, soda, alcohol, bread, trans fats and red meat.

Inflammation is a problem because when your body is in a chronic state of inflammation, the inflammation can lodge in your muscles, joints and tissues. In fact, chronic inflammation is a leading cause of many diseases, both physical and neurological, including heart disease.

So, if you’re interested in keeping your heart healthy without taking drugs, reducing inflammation is an excellent first step, as this will typically naturally put your cholesterol levels into a healthy range. Some top tips to do this are:

  • Eating a healthy diet with plenty of raw fruits and vegetables. Avoid processed foods and buy whole foods whenever possible. Fast food should be only a very occasional indulgence, or not on your diet plan at all, and raw foods should make up a regular part of your meals.

  • Exercising regularly

  • Not smoking

  • Managing stress in your life

  • Limiting alcohol

  • Detoxing regularly. There is some evidence that heart disease (and other chronic illnesses) are caused or exacerabated by an accumulation of heavy metals and other toxins in your body.

    Natural detox products can help you to clean your body of toxic metals and other poisons. Ask your health care practitioner about:
    • Detox Antiox: This formula contains multiple ingredients known to raise glutathione levels making it helpful for supporting phase II liver detoxification. It also combats free radicals and helps detoxify harmful chemicals including heavy metals.

    • Amino-D-Tox™: Designed by clinicians to biochemically upregulate phase II detoxification.

    • Detoxification Support Packets: These packets are the starting point for detoxification programs. One packet contains:

             1 Detox Antiox capsule
             1 LV-GB Complex™ capsule
             3 Amino-D-Tox™ capsules

      • Glutathione Power: Glutathione is one of the most powerful antioxidants known for its ability to protect the body against the damages caused by heavy metal toxicity and environmental toxins. It breaks down wastes, toxins, and heavy metals into less harmful compounds.

Studies confirm link between cholesterol drugs and higher rates of diabetes

Brian Bartholomew - Sunday, July 24, 2011

Studies confirm link between cholesterol drugs and higher rates of diabetes

by Ethan A. Huff, staff writer 

(NaturalNews) Seven years after the American Diabetes Association urged all diabetics, regardless of whether or not they had high cholesterol, to take statin drugs because they "may have some other qualities that have not been tested," (http://www.naturalnews.com/001110.html), a new analysis published in the Journal of the American Medical Association shows that statin drugs actually cause diabetes.

The findings also confirm the general ineptitude of American disease and medical groups that continually push dangerous drugs on the public that have never been adequately verified for safety or effectiveness.

The study, which includes data from five randomized clinical trials, appears poised to highlight the alleged benefits of statins to lower cholesterol levels, rather than focus on their link to causing diabetes.

But what the study actually proves is that taking statins leads to more disease, especially in light of various recent studies that show statins do not even work effectively to lower cholesterol, let alone treat anything else (http://www.naturalnews.com/statins.html).

Despite an slight decrease in cardiovascular events among patients taking statins like Lipitor, Pravachol, and Crestor, the data does not indicate whether other factors like dietary and lifestyle changes may have played a role in this outcome. And yet at the same time, the data shows an 8.4 percent rise in diabetes among the statin groups.

Aside from their many serious side effects, which include loss of muscle mass, liver disease, kidney failure, depleted Coenzyme Q10 levels, and heart attacks, statins have never been proven safe or effective for their stated purpose.

Numerous studies, including one published last year in the British Medical Journal, show that statins harm more people than they actually help -- and in truth, there is scant evidence that statins do anything beneficial at all for patients.

In other words, patients with high cholesterol levels do not need to take statin drugs for the rest of their lives to manage their "condition" -- this is not the only option.

Eliminating processed, chemical-laden foods from your diet, consuming more superfoods like spirulina and chlorella, and getting plenty of daily exercise is a great place to start when trying to lower cholesterol naturally (http://www.naturalnews.com/002692.html).

Sources for this story include:

http://news.yahoo.com/s/afp/2011062...

Just 1 TBSP a Day: An Easy Way to Lower Your Cholesterol, Blood Pressure and...

Brian Bartholomew - Monday, July 18, 2011

Just 1 TBSP a Day: An Easy Way to Lower Your Cholesterol, Blood Pressure and...

Posted By Dr. Mercola | July 17 2011 | 204,446 views

spirulinaBy Dr. Mercola

What if consuming a tablespoon or two per day of a simple food could drastically lower your chances of developing cancer, heart disease or stroke, or of contracting a life-threatening virus such as HIV?

Would your interest be piqued?

There is a unique freshwater plant that has been of enormous interest to nutritional scientists over the past decade, and it shows promise for doing all of the above—and then some. It's one of the most nutrient-packed dynamos of the superfood world.

This simple food is spirulina.

I recently posted a report about the radioprotective effects of spirulina. But its health benefits go far beyond that application. But what exactly is spirulina? You may be surprised!

Spirulina: One of Nature's Near-Perfect Foods




Spirulina is similar to sea vegetables such as dulse, kelp, nori, Kombu, arame, and wakame. Along with its cousin chlorella (another one of my favorites), spirulina is a member of the "blue-green" family—but this family is actually not truly algae.

Although you will often hear the term "blue-green algae," spirulina and its kin are actually cyanobacteria. Cyanobacteria are classified as bacteria because their genetic material is not organized in a membrane-bound nucleus. Unlike other bacteria, they have chlorophyll and use the sun as an energy source, in the way plants and algae do.

Spirulina is primarily produced by two species: Arthrospira platensis and Arthrospira maxima.

One of the special traits of spirulina is its rich protein content—it's 50 to 70 percent protein by weight and contains all of the essential amino acids. Records of the Spanish conquistadors suggest that the Aztecs consumed spirulina as a food source, and the Kanembu people of Central Africa harvested it from what is now called Lake Chad.

Wild spirulina grows in the alkaline lakes of Mexico and on the African continent, although it is commercially grown and harvested all over the world. It reproduces quickly, and because the individual organisms tend to clump together, it's easy to harvest. Commercial production of spirulina is estimated to reach 220,000 tons by the year 2020. Japan is the largest producer of spirulina, as well as the largest consumer.

Spirulina Packs Quite a Nutritional Punch




Spirulina is one of the most nutritious and concentrated food sources on the planet. As a result, it's appearing more frequently all the time in natural foods and beverages, such as green foods and drinks, energy bars and oral supplements.

Spirulina consistently boasts an amazing protein level of 60 percent on average—even better than red meat, which is about 27 percent protein. And spirulina's protein is biologically complete, containing all of the essential amino acids needed for human health. Spirulina also contains a potent array of other beneficial nutrients, including the following:

B vitamins (including exceptionally high B-12), vitamin K, and other vitamins Naturally rich in iodine Minerals (including calcium, iron, magnesium, selenium, manganese, potassium, and zinc)
One of best known sources of gamma-linolenic acid (GLA, an important fatty acid for heart and joints) Other essential fatty acids, including sulfolipids, which may be protective against HIV infection of T-helper cells Phytopigments (phycocyanin, chlorophyll, and carotenoids)
Metallo-thionine compounds (proteins combined with metals that bind heavy radioactive isotopes) Low in carbohydrates (15-20 percent) Eighteen different amino acids

(For specific concentrations of the above-mentioned nutrients in spirulina, refer to Table 1 in this spirulina report by S. Thomas of Parry Nutraceuticals.) In addition to this rich nutritional blend, spirulina has the following special properties:

  • The proteins in spirulina are of a highly digestible type (83 to 90 percent digestible), due to the fact that it does not have cellulose walls, like yeast and chlorella do. Therefore, the net protein utilization (NPU) is high (between 53 and 61 percent) and requires no cooking to increase the bioavailability of its proteins.
  • Studies confirm a very high "protein efficiency ratio" (PER) for spirulina, meaning your body will be able to efficiently use these amino acids.
  • Gamma-linolenic acid is rarely this high in ANY food and normally has to be synthesized by your body from linoleic acid. GLA is a precursor to important biochemicals such as prostaglandins, leukotrienes, and thromboxanes, which serve as chemical mediators for inflammatory and immune reactions.
  • Spirulina has no fatty acids with uneven carbon numbers and very low-level branched-chain fatty acids—two types of lipids that higher order animals, like you and me, cannot metabolize.
  • Spirulina has about the same calcium, phosphorous, and magnesium content as milk, a vitamin E (tocopherol) level comparable to wheat germ, and four times as much vitamin B12 as raw liver!

Research-Based Health Benefits of Spirulina

Now that you have spirulina's nutritional overview, let's take a look at what this unique blue-green cyanobacteria can do for your health. The health benefits of spirulina continue to be widely researched. As a result, there is really no way to cover all of the literature related to its potential benefits because there are so many!  There are scientific studies supporting spirulina's potential usefulness in preventing and/or treating the following health conditions:

ARMD (Age-related macular degeneration) Type 2 Diabetes
Cardiovascular disease, including hypertension NAFLD (Non-alcoholic fatty liver disease)
Liver health and decreased damage from heavy metal exposure Cerebrovascular disease (including stroke)
Nutritional diseases, such as iron deficiency anemia, pernicious anemia (B12 deficiency), vitamin A deficiency, and kwashiorkor Neurodegenerative disorders such as Parkinson's and Alzheimer's
Protection from HIV and other viruses Reduced allergy symptoms
Cancer protection Radiation protection (LINK to recent spirulina radiation article)
Bone marrow and blood health (especially during use of anticancer drugs) Strengthening immune defenses and modulating inflammatory response
Reduced pain sensitivity by inhibiting prostaglandins, which contribute to pain and inflammation Reduction of arthritis symptoms
Protection from the damage of ionizing radiation

As you can see, the health benefits of spirulina are truly far-ranging.  The remainder of this report will focus on how spirulina can address some of the diseases listed in the above table (the ones shown in bold).

Spirulina and Your Eyes

As the population ages, the prevalence of Age-Related Macular Degeneration (ARMD) is on the rise. ARMD is the deterioration of your macula (the region in your eye that controls acute vision), which typically occurs later in life.  ARMD is the leading cause of blindness today.

Your eyes' macular membranes contain several carotenoid pigments called xanthophylls—lutein, zeaxanthin, and possibly astaxanthin, if you're getting it as part of your diet. These special pigments help protect your eyes from damage by slowing down ultraviolet-induced oxidation of lipid membranes, thereby helping prevent degeneration of your macula.

Additionally, xanthophylls may be effective in preventing cataracts. Spirulina provides 3,750 to 6,000 mcg zeaxanthin per serving size (3 grams). Eggs are another excellent source of both lutein and zeaxanthin (200mcg zeaxanthin per yolk). Astaxathin is also another marine based nutrient that is in the carotenoid family and is also a potent preventor of ARMD.

Spirulina and Type 2 Diabetes

Type 2 diabetes is an epidemic in the Western world today. It is really a cluster of related pathologies, including insulin resistance, obesity, dyslipidemia and hypertension. Spirulina has been shown to benefit diabetics in the following ways:

  • Reducing systemic inflammation. (Insulin resistance has come to be associated with a state of systemic low-grade inflammation.)
  • Favorably altering your lipid profile by reducing serum triglycerides and increasing HDL.
  • Improving vasodilation in those who are obese as a result of high fructose diets (which has benefits for diabetics, as well as for those with hypertension and cardiovascular disease).

Spirulina and Your Cardiovascular Health

Diabetes and cardiovascular health are intimately connected, so it's no surprise that spirulina shows great potential for people with cardiovascular disease, in terms of creating better lipid profiles, controlling hypertension, and increasing blood vessel elasticity. Diabetic patients given 2 grams per day of spirulina showed improved glycosylated hemoglobin and better lipid profiles in this 2001 study. And in this study of the Mexican population, 4.5 grams per day of spirulina significantly reduced serum triglyceride levels and total cholesterol, boosted HDL, and reduced blood pressure in test subjects.

It is thought that the lipid action of spirulina may be due to its phycocyanin content, which inhibits pancreatic lipase activity, and this in turn causes higher excretion of triglycerides through your feces.

In one animal study, spirulina prevented hypertension and vasoconstriction in rats fed fructose-rich diets, but rats fed fructose-rich diets without spirulina had those adverse health effects. Hamsters consuming spirulina were protected from developing atherosclerosis inthis 2007 study.

Spirulina and Your Liver

The accumulation of fats in your liver is closely associated with metabolic syndrome and strongly raises your risk for dying from cardiovascular disease. Non-alcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease in North America and notoriously difficult to treat, at least with traditional medical measures.

Animal studies suggest spirulina can protect your liver, probably as a result of its high antioxidant properties and its ability to synthesize or release nitric oxide. Studies show that spirulina does the following for your liver:

  • Prevents the buildup of triglycerides in your liver
  • Inhibits lipid peroxidation
  • Reduces liver inflammation
  • Protects your liver from damage by heavy metals, like lead and mercury

Spirulina and Your Brain

The third leading cause of death in the U.S. is stroke. Diets high in antioxidants have been shown to lower your risk for stroke. Two studies (one in the Journal of Agricultural and Food Chemistry, the other in the British Journal of Nutrition) showed that Spirulina reduces platelet aggregation, which plays an important role in vascular diseases by reducing your risk for thromboembolism.

In another study, three antioxidant-rich diets (blueberries, spinach, and spirulina) were compared for their neuroprotective effects. Spirulina was found to have the highest neuroprotective effect, possibly due to its ability to squelch free radicals and reduce inflammation.

And in an Oregon State University study of rats that had induced strokes, the group fed spirulina showed brains lesions that were 75 percent smaller than those in control groups.

Oxidative stress is one major source of inflammation, and in your brain, it can result in loss of dopamine neurons and lead to neurodegenerative disorders such as Parkinson's and Alzheimer's. An enzyme complex called NADPH oxidase has been shown to play a role in these diseases, and the phycocyanin in spirulina can suppress NADPH oxidase, lowering your risk for these age-related brain diseases. (I will go into this further in the next section.)

In animal studies, diets enriched with spirulina were found to reverse the inflammation that can lead to diminished neurogenesis (production of new neurons), which is another factor in degenerative diseases of the brain. Bob Capelli, of Cyanotech Corporation said:

"Spirulina has long been associated with immune building and anti-viral properties, eye and brain health and cardiovascular health, but we now see that spirulina also has anti-inflammatory properties through this research on one of the principal constituents in spirulina, phycocyanin. This study isolates the mechanism of action for phycocyanin as an anti-inflammatory."

Let's look a little more at the antioxidant properties of spirulina—in particular, its special pigmented component, phycocyanobilin.

The Spirulina-Bilirubin Connection

Phycocyanobilin contained in spirulina is a close chemical relative of bilirubin. In mammalian cells, phycocyanobilin is converted into phycocyanorubin, a compound nearly identical to bilirubin. Bilirubin is the chemical responsible for the yellow color of bruises, urine, and jaundice and occurs as a breakdown product of your red blood cells (heme). When a newborn baby gets jaundice, he is placed under "bili lights" in the hospital nursery to prevent brain damage (kernicterus), if his bilirubin levels become too high. The lights break down the bilirubin so it can be excreted.

But bilirubin, at appropriate levels, has a strong free radial scavenging effect.

Until recently, scientists were not aware that bilirubin may actually have anti-inflammatory, antioxidant, and atheroprotective properties—and there is a growing body of scientific and clinical evidence to support this. From an evolutionary/biological perspective, it makes sense that nature would have created a way for your body to break down heme, which can be toxic if it accumulates.

The way bilirubin is thought to provide these health benefits is through its ability to inhibit NADPH oxidase, a metabolic enzyme that is activated in a large number of pathological conditions and generates a great deal of oxidative stress in your body. In fact, NADPH overactivity appears to play a significant roll in a wide range of adverse health conditions, including but not limited to the following:

  • Vascular diseases and vascular complications of other diseases (diabetes, kidney failure, blindness, heart disease, etc.)
  • Insulin resistance
  • Neurodegenerative disorders, like Alzheimer's and Parkinson's
  • Many human cancers
  • Glaucoma
  • Pulmonary fibrosis
  • Erectile dysfunction

NADPH seems to be a chemical that can be helpful or harmful, depending on how much of it is circulating at the time, so it needs to be carefully regulated by your body. For example, NADPH oxidase plays a key role in helping your immune system fight bacteria and helps your T-cells to function properly.

It follows then that preventing many chronic diseases would require finding a means of inhibiting or modulating NADPH oxidase.

Bilirubin is now believed to assist with this modulating effect.

People with Gilbert Syndrome comprise 5-10% of the population and illustrate this phenomenon very nicely—they are genetically predisposed to chronically elevated levels of unconjugated bilirubin. These individuals, having two to three times as much bilirubin as the rest of us, enjoy a greatly reduced risk for coronary artery disease, hypertension and carotid atherosclerosis, and these protections are thought to be related to their high bilirubin levels.  I happen to be one of those with Gilbert's and did not realize until reviewing the research for this article that my elevated bilirubin levels were actually a major benefit.

Since phycocyanobilin is a very close relative of bilirubin—and spirulina is a great source of phycocyanobilin—spirulina has enormous clinical potential due to its NADPH oxidase inhibiting effect. This is why phycocyanobilin has been the focus of a large amount of research of late. Phycobilin extracts have been shown to inhibit NADPH oxidase activity in human aortic endothelium, aortic smooth muscle, and renal cell cultures. And bilirubin protects against diabetic nephropathy via downregulation of NADPH oxidase in rats.

Concluding Remarks

The scientific evidence for spirulina's health benefits is abundant, frequently showing remarkable clinical results. And spirulina's safety is equally impressive! Rodents show no ill effects when fed diets very high in Spirulina. And remember, it was a major component of the Aztec diet.

Spirulina is even good for your pet (be he dog, cat, bird, fish or reptile) promoting a strong immune system, a healthy coat, heart and joint health, and even fresher breath—which is why I now offer SpiruGreen Superfood for Pets. It appears this is a near-perfect food for everyone in your family—one more natural way to take charge of your health.

Sources:

Statin Drugs May Shorten Life

Brian Bartholomew - Friday, May 27, 2011

Statins Do Not Extend Life, Not Even By A Day

by Heidi Stevenson

4 August 2009Skull & Crossbones filled with pills

There's data missing from nearly all statin studies—death rates from all causes. The true indicator of whether these drugs extend life is not included in most statin studies.

The goal in taking any drug is to live better and longer. That should be obvious. Reality, though, doesn't necessarily match reason, and statins are a prime example. Most are prescribed and taken by people with no history of heart disease. There's a push now to have nearly everyone over age 40 or 50, or with cholesterol levels above a certain point—a level that includes nearly everyone over the age of 25 or so—to take statins.

The American Academy of Pediatrics now pushes for cholesterol screening of all children, with drug treatment for any child whose levels are over their definition of normal cholesterol. Since cholesterol levels that are too low harm mental functioning,(1) consider what this might mean for children's mental development.

Obviously, though, since the APA recommends putting children on statins and the consensus seems to be that statins are needed by the vast majority of adults, this must mean that statins will make you live longer...right?

No! There isn't one shred of evidence that taking statins extends life by a single day in people who don't have active heart disease. They are brilliantly successful, though, in extending the size of pharmaceutical companies' pockets.

How is this sleight of hand achieved? It's the trickery of statistics and choosing which data to report. You don't really believe that most modern medical studies reveal all the data, do you?

Statin Research Prestidigitation

Modern medical studies use a wide array of techniques to skew the results. One of the best ways to confuse things is by not offering all the data. It may seem that not including data would be so obvious that no one could get away with it. It is, though, one of the easiest tricks to pull off.

Saving Lives?

Where do all the statistics proclaiming life saving benefits of statin use come from? Magic, of course—the magic of picking and choosing which information to include in a study report, and presenting information in a manner that misleads. The point of this article isn't to examine all the methods studies use to trick us into believing that treatments and pharmaceuticals are effective. We'll focus on the two primary techniques used in statin trials:

  • Ignoring deaths from all causes.
  • Presenting life extension data out of context.

Ignoring Deaths From All Causes

The first method, ignoring deaths from all causes, is quite routine. Dr. Malcolm Kendrick, in his book, The Great Cholesterol Con, refers to this as the elephant "sitting in the middle of the room...quietly cleaning its tusks". He calls this elephant, "Nellie the total mortality data". He reports on his inability to get total mortality data from researchers.

Dr. Kendrick colorfully described how focusing on only one cause of death can twist study results:

If I ran a clinical trial in which I gave half the people a lethal dose of botulinum toxin, and gave the other half a placebo. I would reduce the rate of death from CV diseases to zero in botulinum group.
I could then claim that botulinum toxin provides complete protection against heart disease, as no-one in this group died of a heart attack. However, the statistics on overall mortality might not look so good.
In a less extreme version, if you give high dose statins to half the population and this prevents death from CV disease……so what, if all you have done is to change what is written on the death certificate, not the date.(1)

Presenting Life Extension Data Out of Context

The second method of obfuscating statin research results, presenting life extension data out of context, is a bit more difficult to describe. First, note that there is a group of people who do benefit from statins. These are generally older men who have existing heart disease.

The unit generally used in statin trials is "lives saved". It sounds good, but what does it mean? Let's take, as an example, the claim made regarding the HPS study, which focused on patients at very high risk of death from heart disease, not people whose blood levels are over an arbitrary level. It said that 50,000 lives would be saved every year if 10 million people went onto statin treatment. That translates into 1 person out of 200 - not quite as impressive as "50,000 lives saved". But even that relatively small number doesn't present the full truth.

Note: Women have not been shown to benefit from statins, period. With or without existing heart disease, statins do not provide benefit to women.

What really matters is how taking statin drugs will affect your life. Statins don't prevent death. At best, they may put it off. So "lives saved" doesn't have much meaning. The real question is how much longer people live. So, let's take another look at the real meaning of saving the life of 1 person in 200 each year.

This statistic actually means that, if people at high risk from heart disease take statins for one year, then the average extension in life would be less than two days. It's not so impressive when you look at it this way—but this is the realistic view. The real issue is the personal effect of taking them. Would your life be saved? In fact, it would not. Is there a good chance your life would be extended? Yes. If you are at high risk of death from heart disease, after a year of taking statins, the odds are that you would live two more days. Are you impressed?

If presenting the effectiveness of statins in this way seems like another way of twisting stats, consider that this is how studies in cancer present results. It's in terms of life extension, not lives saved. What matters is the effect on you, and that can better be measured in the likelihood of extending life, not in terms of lives saved.

Do Statins Extend Life in People Without Heart Disease?

It's a bit tougher to examine the question of whether statins extend life in people who haven't exhibited signs of heart disease. The primary point to note is that most studies do not include overall mortality figures. Without these, it's impossible to be sure. However, one must question why such data are not included. If they did demonstrate that people live longer by taking statins, wouldn't that information be included?

Nonetheless, one intrepid researcher did manage to do a study of results from pre-existing trials on statin use, including those with heart disease and those without it. Dr. Graham Jackson reviewed nearly all statin studies done before 2000. He reported in the British Journal of Clinical Pharmacology:

Long term use of statins for primary prevention of heart disease produced a 1% greater risk of death over ten years vs placebo when the result of all the big controlled trials reported before 2000 were combined.

There is no valid documentation showing that taking statins is of any value in people who do not have heart disease. In truth, statins can do great harm, as documented in Statins Send Minds Down the Memory Hole, which focuses on memory loss, but also touches on other risks associated with them. While it is true that men—and only men—with pre-existing heart disease, such as those who have already had heart attacks, may benefit from taking statins, there is no justification for their use in anyone else.

It is true that statins can reduce serum cholesterol, and quite significantly. This, though, does not translate into protection against heart disease. To understand why, read Cholesterol Doesn't Cause Heart Disease

Instead of the headlong push into taking statins, treating them as if they were no riskier than taking a placebo, it's time to put a halt to the insanity.


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